This talk will discuss the opportunities for innovation in microTESE negative non-obstructive azoospermic males. We will discuss opportunities for applying image-based machine learning for sperm identification following microTESE. We will also discuss a personalized and precision medicine framework aiming to overcome cellular dysfunction and promote regeneration of spermatogenesis using single cell sequencing, development of novel culture methods, use of human induced pluripotent stem cells and 3D bioprinting.
Mice are the most commonly used animal model for studying human disease. However, in the reproductive biology area, its use has always presented the problem of obtaining in vivo sperm samples. The technique described in this webinar allows the serial extraction of sperm samples, facilitating the use of the mouse as a research tool.