Gene Editing in Domestic Animals

Description:
This special topics SSR webinar will focus on the current state of genetic modifications in agriculture. Especially, how gene editing has been harnessed in reproductive biology to address health and productivity challenges in livestock, with a focus on the poultry, pork, and beef industries. Discussion will highlight both recent successes and outstanding hurdles. Topics will also be held the context of regulatory policies, social appetite, and food security.

Moderator:
Michela Ciccarelli, DVM, MS, PhD, Dipl. ACT
Assistant Professor
Comparative Theriogenology
Veterinary Clinical Sciences
College of Veterinary Medicine
Washington State University

Panelists:
Jon M. Oatley, PhD
Associate Dean for Research
Professor, School of Molecular Biosciences
Director, Functional Genomics Initiative
College of Veterinary Medicine
Washington State University

Mike McGrew, PhD
Personal Chair of Avian Reproductive Technologies (ART)
The Roslin Institute
Easter Bush Campus
University of Edinburgh

Genetic Engineering Via Mammalian Zygotes

Since genetically modified animals are helpful for functional analysis of gene or genome information, they are widely used in various life science studies, including Reproductive Biology. With the recent development of genetic modification tools, such as the CRISPR/Cas system, it is now possible to perform genetic modification via zygotes, which was once only possible using ES cells. This talk will introduce the technologies the speaker has reported or is under development.

Gene Editing in Primates

Recently developed gene-editing techniques have revolutionized our ability to create valuable models of disease. Dr. Jon Hennebold talks about research efforts to use gene-editing approaches for the creation of nonhuman primate disease models that will be critical for understanding their pathology as well as the development of novel therapies.

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