Speaker: Dr. David Pépin, Harvard Medical School
Title: Development of a new non-hormonal contraceptive targeting the AMH/AMHR2 axis in females.
Description: Anti-Müllerian hormone (AMH) is a paracrine factor produced by growing follicles that mediates negative feedback on the activation and growth of new pre-antral follicles. Sustained supraphysiological AMH can suppress follicular development and induce contraception. Herein we will present findings on the mechanism of action of AMH in follicles, the development of new contraceptive modalities including gene therapy with AMH and small molecule agonists of the AMH receptor (AMHR2), and their evaluation in several animal models from mice to cats.
The Laramie Foothills Bison Conservation Project focuses on the ecologic and reproductive wellbeing of the bison herd at CSU. Today, we are talking to Dr. Jennifer Barfield and Dr. Kate Wilkins about what it takes to manage, breed, and conserve a bison herd. Tune in as we talk about the importance of bison in their habitat, the benefits of ART, the cultural importance behind this species, and why it takes a village to bring together this project. Enjoy!
Today’s episode is about Dr. Crosier, the director of the cheetah reproductive and research program at the Smithsonian’s National Zoo and Conservation Biology Institute (SCBI). Tune in as we talk about her journey into the exotic reproductive field, challenges associated with ART in big cats, other projects happening at SCBI, and of course all things felid reproduction!
