OoCount: A Machine-Learning Based Approach to Mouse Ovarian Follicle Counting and Classification Share

Speaker: Jennifer McKey, PhD, University of Colorado Anschutz Medical Campus

Description: The number and distribution of ovarian follicles in each growth stage provides a reliable readout of ovarian health and function. During this webinar, we will provide step-by-step instructions to apply and customize OoCount. OoCount is a high-throughput, open-source method for automatic oocyte segmentation and classification from fluorescent 3D images of whole mouse ovaries using a deep-learning convolutional neural network (CNN) based approach.

Opportunities for Innovation in microTESE Negative Males With Non-Obstructive Azoospermia

This talk will discuss the opportunities for innovation in microTESE negative non-obstructive azoospermic males. We will discuss opportunities for applying image-based machine learning for sperm identification following microTESE. We will also discuss a personalized and precision medicine framework aiming to overcome cellular dysfunction and promote regeneration of spermatogenesis using single cell sequencing, development of novel culture methods, use of human induced pluripotent stem cells and 3D bioprinting.

Retinoic acid synchronization of spermatogenesis

This webinar will discuss synchronization of spermatogenesis by manipulating retinoic acid availability is an advantage for molecular studies of the cycle of the seminiferous epithelium and for isolation of germ and Sertoli cells at different stages of development.

Serial sampling of epididymal sperm in mice

Mice are the most commonly used animal model for studying human disease. However, in the reproductive biology area, its use has always presented the problem of obtaining in vivo sperm samples. The technique described in this webinar allows the serial extraction of sperm samples, facilitating the use of the mouse as a research tool.

Dr. Barfield, Dr. Wilkins, and the Laramie Foothills Bison Conservation Herd Project!

The Laramie Foothills Bison Conservation Project focuses on the ecologic and reproductive wellbeing of the bison herd at CSU. Today, we are talking to Dr. Jennifer Barfield and Dr. Kate Wilkins about what it takes to manage, breed, and conserve a bison herd. Tune in as we talk about the importance of bison in their habitat, the benefits of ART, the cultural importance behind this species, and why it takes a village to bring together this project. Enjoy!

Genetic Engineering Via Mammalian Zygotes

Since genetically modified animals are helpful for functional analysis of gene or genome information, they are widely used in various life science studies, including Reproductive Biology. With the recent development of genetic modification tools, such as the CRISPR/Cas system, it is now possible to perform genetic modification via zygotes, which was once only possible using ES cells. This talk will introduce the technologies the speaker has reported or is under development.

The impacts of IVF and other Assisted Reproductive Technologies (ART) on human reproduction with Dr Rebecca Krisher

This is the second episode in our series on Breakthroughs in Reproductive Technologies. Here Dr Jane Fenelon and Dr Rachel West talk to Dr Rebecca Krisher about the impact that Assisted Reproductive Technologies (ART) have had on human reproduction. Join us as we learn more about the common procedures that are available to us today and their efficacy and about some of the controversies surrounding ‘add-ons’ on offer in the IVF clinic We also try and answer some of the big questions like when should women start thinking about their fertility? And what does the future hold? As well as a fascinating insight into Rebecca’s career journey so far and tips for trainees.

Dr. Crosier: Fertility studies and Reproductive Management in Cheetahs!

Today’s episode is about Dr. Crosier, the director of the cheetah reproductive and research program at the Smithsonian’s National Zoo and Conservation Biology Institute (SCBI). Tune in as we talk about her journey into the exotic reproductive field, challenges associated with ART in big cats, other projects happening at SCBI, and of course all things felid reproduction!

Breakthroughs in Reproductive Technologies: The history of Assisted Reproductive Technologies (ART) in agriculture with Dr Peter Hansen, Part 1

The first in our series on Breakthroughs in Reproductive Technologies. Here Dr Jane Fenelon and Dr Jean-Magloire Feugang interview Dr Peter Hansen on the history of Assisted Reproductive Technologies (ART) and the significant impacts its had on the Agricultural Industry. In Part 1 learn what we mean when we talk about ART technologies and about the pioneers in the field who were instrumental in setting up these technologies. 

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