Description: Join us for the first webinar of SSR’s New Investigator Bootcamp series, titled “Finding, Applying to, and Negotiating Your First Faculty Position”. This session is tailored toward future investigators seeking their first independent positions and features an expert panel, including Dr. Farners Amargant i Riera, Dr. Andrew Modzelewski, Dr. Ky Pohler, Dr. Joanie Jorgensen, and Dr. Carmen Williams.
Resource Category: Education
Interview with 2022 Fuller W Bazer SSR International Scientist Awardee, Dr Moira O’Bryan, University of Melbourne
Intverview with 2022 SSR Trainee Mentoring Awardee Dr. Thomas Curry
Interview with 2022 SSR Janice Bahr Junior Scientist Travel Awardee Dr. Joe (Huanyu) Qiao
Sex-differences in immune aging: are we missing half of the picture?
Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are short-lived cells, and thus the impact of organismal aging on neutrophil biology, especially as a function of biological sex, remains poorly understood. We have generated a multi-omic resource of mouse primary bone marrow neutrophil from young and old female and male mice, at the transcriptomic, metabolomic and lipidomic levels. We identified widespread regulation of neutrophil ‘omics’ landscapes with organismal aging and biological sex. In addition, we leveraged this data to predict functional differences, including changes in neutrophil responses to activation signals. To date, this dataset represents the largest multi-omics resource for neutrophils across sex and ages. This resource identifies neutrophil characteristics which could be targeted to improve immune responses as a function of sex and/or age.
Mom’s sleep matters! Impact of sleep apnea during pregnancy on offspring brain function
New Non-hormonal Contraceptive Targets
These webinars, sponsored by the Society for the Study of Reproduction (SSR), Frontiers in Reproduction (FIR), and the Bill & Melinda Gates Foundation, will focus on emerging technologies and approaches to male and female contraception.
Speakers:
Dr. Lonny R. Levin, Professor of Pharmacology, Weill Cornell Medical College
Read more about Dr. Levin’s Presentation
Title: On-demand nonhormonal male contraception via ADCY10 inhibition
Description: Fast-acting sAC inhibitors with slow off-rates can provide safe, pre-coital, on-demand contraception for men which is nonhormonal, orally available, easily tolerated, fast-acting, and readily reversible.
Dr. Celia Santi, Associate Professor of OBGYN, Washington University School of Medicine in St. Louis
Read more about Dr. Santi’s presentation!
Title: Targeting the sperm-specific K+ channel SLO3 for non-hormonal contraception.
Description: Identification of inhibitors of the sperm specific SLO3 K+ channel that can be developed into a non-hormonal class of female contraceptives that act by targeting sperm capacitation.
Developing New Methods for Testing, Studying, and Delivering Contraception
These webinars, sponsored by the Society for the Study of Reproduction (SSR), Frontiers in Reproduction (FIR), and the Bill & Melinda Gates Foundation, will focus on emerging technologies and approaches to male and female contraception.
Speakers:
Dr. Jianjun Sun, Associate Professor, Department of Physiology & Neurobiology, University of Connecticut, Storrs
Read more about Dr. Sun’s Presentation
Title: Screening female contraceptive compounds using Drosophila ovulation model
Description: In my presentation, I will introduce the ovulation mechanism in Drosophila and describe the platform utilizing Drosophila ovulation to screen contraceptive compounds that can effectively inhibit follicle rupture.
Dr. Phil Santangelo, Associate Professor of Biomedical Engineering, Georgia Tech University & Emory University
Read more about Dr. Santangelo’s Presentation
Title: Intravaginal delivery of mRNA encoded contraceptive antibodies
Interview with 2022 SSR New Investigator Awardee Dr. David Pepin
Today’s interview is all about Dr. David Pepin the winner of the 2022 SSR New Investigator Award. Listen close as we talk about his career journey, the challenges he’s faced as a postdoc, and all about his research on female reproductive health.
Novel bidirectional pathways in the hypothalamic control of reproduction and metabolism
In this presentation I will be covering the novel pathways in which Kiss1 neurons participate in the bidirectional regulation of energy balance and reproduction. In particular, I will talk about novel transcription factors involved in this regulatory process and offer evidence supporting a role for Kiss1 neurons in the mediation of the reproductive and metabolic role of melanocortins.